Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 9/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23100937 | 0.78 | HTT (0.44) | NPY5RHTTPDE10ADRD4DRD2 | |
| SCHEMBL18138868 | 0.78 | TNKS (0.48) | OPRM1OPRK1OPRL1 | |
| SCHEMBL16618821 | 0.70 | CNR1 (0.54) | DRD4POLBOPRM1OPRK1OPRL1 | |
| SCHEMBL17781438 | 0.69 | PDE10A (0.41) | HTTPDE10ADRD4DRD2HPGD | |
| SCHEMBL7745407 | 0.69 | PDE10A (0.53) | NPY5RHTTPDE10ADRD4DRD2 | |
| SCHEMBL5157052 | 0.68 | HTT (0.84) | HTTDRD4DRD2HPGDOPRK1 | |
| SCHEMBL3178585 | 0.68 | OPRL1 (0.59) | OPRM1OPRK1OPRL1 | |
| SCHEMBL10518420 | 0.67 | OPRL1 (0.49) | OPRM1OPRK1OPRL1 | |
| SCHEMBL16812348 | 0.67 | OPRL1 (0.48) | OPRM1OPRK1OPRL1 | |
| SCHEMBL30181583 | 0.67 | OPRL1 (0.45) | OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10030029-B2 | Imidazole derivative used as antiviral agent and use thereof in preparation of medicament | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. (CN) | 2018-07-24 | — | — | US | disclosed |
| US-9850251-B2 | Imidazole derivative used as antiviral agent and use therof in preparation of medicament | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. (CN) | 2017-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030029-B2 | Imidazole derivative used as antiviral agent and use thereof in preparation of medicament | MAVS, ZC3HAV1, SARS1 | NPY5R 4753/4885HTT 4491/4885PDE10A 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.