Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | MPI | P34949 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720966 | 0.74 | NPSR1 (0.79) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL5864478 | 0.73 | ALDH1A1 (0.64) | PDE10AALDH1A1DRD4POLB | |
| SCHEMBL12202119 | 0.71 | ALDH1A1 (0.68) | PDE10AALDH1A1TDP1DRD4DRD2 | |
| SCHEMBL27864664 | 0.70 | PDE10A (0.53) | PDE10AALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL19749938 | 0.69 | NPY5R (0.51) | PDE10AHPGDHTTDRD4DRD2 | |
| SCHEMBL11373746 | 0.69 | UBE2N (0.76) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL9290311 | 0.69 | UBE2N (0.68) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL6270684 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL9720971 | 0.69 | HPGD (0.70) | ALDH1A1HPGDCASP1MPICACNA1B | |
| SCHEMBL29437299 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HPGDCASP1MPICACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |