SCHEMBL19749977

SCHEMBL19749977

CCCOc1cc(O)cc2oc(-c3ccc(O)cc3)c(O)c(=O)c12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 6/20 0.61
CYP1A1 P04798 5/20 0.61
CYP1A2 P05177 5/20 0.61
CYP1B1 Q16678 5/20 0.61
FTO Q9C0B1 3/20 0.61
MEN1 O00255 3/20 0.61
CA12 O43570 3/20 0.61
PPARG P37231 3/20 0.61
CA7 P43166 3/20 0.61
XDH P47989 3/20 0.61
KMT2A Q03164 3/20 0.61
NOX4 Q9NPH5 2/20 0.61
CA2 P00918 2/20 0.61
IPMK Q8NFU5 2/20 0.61
IP6K2 Q9UHH9 2/20 0.61
ABCG2 Q9UNQ0 2/20 0.61
BCHE P06276 2/20 0.61
CYP3A4 P08684 2/20 0.61
CYP2D6 P10635 2/20 0.61
MAPT P10636 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15635189 0.84 NOX4 (0.79) ABCB1CYP1A1CYP1A2CYP1B1FTO
SCHEMBL22107815 0.83 ABCB1 (0.55) ABCB1CYP1A1CYP1A2CYP1B1FTO
SCHEMBL18102778 0.82 ABCB1 (0.56) ABCB1CYP1A1CYP1A2CYP1B1FTO
SCHEMBL12693921 0.80 ABCG2 (0.62) ABCB1CYP1A1CYP1A2CYP1B1FTO
Nonacosane SCHEMBL28207166 0.78 ABCB1 (0.83) ABCB1CYP1A1CYP1A2CYP1B1FTO
SCHEMBL28757172 0.78 ADORA3 (0.60) ABCB1CYP1A1CYP1A2CYP1B1FTO
Kaempferol SCHEMBL15634534 0.77 MEN1 (0.89) ABCB1CYP1A1CYP1A2CYP1B1FTO
SCHEMBL13620318 0.77 MEN1 (0.74) ABCB1CYP1A1CYP1A2CYP1B1FTO
Kaempferol SCHEMBL1259228 0.76 MEN1 (1.00) ABCB1CYP1A1CYP1A2CYP1B1FTO
Kaempferol SCHEMBL30655455 0.76 MEN1 (1.00) ABCB1CYP1A1CYP1A2CYP1B1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9850221-B2 Sulfated and unsulfated flavonoid oligomers as cancer therapeutics VIRGINIA COMMONWEALTH UNIVERSITY (US) 2017-12-26 US disclosed