Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19752032 | 0.87 | ACHE (0.40) | ACHEQPCTMDM2TP53USP2 | |
| SCHEMBL1713661 | 0.70 | QPCT (0.41) | ACHEQPCTMDM2TP53USP2 | |
| SCHEMBL1713833 | 0.69 | QPCT (0.41) | ACHEQPCTMDM2TP53CCR1 | |
| SCHEMBL466453 | 0.69 | TP53 (0.48) | MDM2TP53TSHRALDH1A1 | |
| SCHEMBL5562887 | 0.62 | HTT (0.43) | ACHEHTTMAPTCACNA1FCACNA1D | |
| SCHEMBL8566011 | 0.61 | MEN1 (0.61) | ACHETP53LMNA | |
| SCHEMBL10688067 | 0.57 | GAA (0.55) | LMNATSHRALOX15ALDH1A1HPGD | |
| SCHEMBL2984488 | 0.57 | QPCT (0.37) | QPCTTSHRALDH1A1HPGD | |
| SCHEMBL25420635 | 0.56 | LMNA (0.44) | QPCTLMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL11523039 | 0.56 | MEN1 (0.63) | TP53MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344158-B1 | USE OF ISOQC INHIBITORS | PROBIODRUG AG (DE) | 2017-12-27 | — | — | EP | disclosed |