SCHEMBL197522

SCHEMBL197522

COc1ccc(-c2ccc(OC)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.79
CA2 P00918 2/20 0.79
CA7 P43166 2/20 0.79
CA9 Q16790 2/20 0.79
CA12 O43570 1/20 0.79
CA14 Q9ULX7 1/20 0.79
ESR2 Q92731 1/20 0.74
MAPK1 P28482 3/20 0.64
NPC1 O15118 2/20 0.64
RAB9A P51151 2/20 0.64
TP53 P04637 2/20 0.64
CASP3 P42574 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
SENP8 Q96LD8 1/20 0.64
SENP7 Q9BQF6 1/20 0.64
SENP6 Q9GZR1 1/20 0.64
APP P05067 1/20 0.62
ACHE P22303 1/20 0.61
MAOB P27338 2/20 0.58
ABL1 P00519 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6733562 1.00 CA1 (0.79) CA1CA2CA7CA9CA12
SCHEMBL9151672 1.00 CA1 (0.79) CA1CA2CA7CA9CA12
SCHEMBL13038584 0.91 LTA4H (0.67) CA1CA2CA7CA9CA12
SCHEMBL920933 0.91 ABL1 (0.71) CA1CA2CA7CA9CA12
SCHEMBL3743494 0.91 ABL1 (0.71) CA1CA2CA7CA9CA12
SCHEMBL7610770 0.91 LTA4H (0.67) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.89 CA1 (1.00) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL21802643 0.89 CA1 (1.00) CA1CA2CA7CA9CA12
SCHEMBL12714843 0.88 ACHE (0.83) CA1CA2CA7CA9CA12
SCHEMBL17283658 0.88 CA4 (0.68) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080343-A Method for synthesizing polyarylketone compound 2026-05-26 CN claimed
CN-119092798-A MOF-based solid electrolyte composite membrane and preparation method and application thereof 浙江大学杭州国际科创中心 2024-12-06 CN claimed
CN-118125989-A Method for synthesizing triphenylene derivative containing triazine structure 棓诺(苏州)新材料有限公司 2024-06-04 CN claimed
CN-114874591-B Conductive super-crosslinked conjugated polymer electromagnetic wave absorbing material and preparation method thereof 中国船舶重工集团公司第七二五研究所 2024-01-30 CN claimed
US-11844842-B2 Composition of polyethylene glycol maleimide derivative and polymerization inhibitor JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) 2023-12-19 US claimed
CN-117143348-A Metal-MOF composite material and preparation method and application thereof 浙江大学杭州国际科创中心 2023-12-01 CN claimed
CN-115094463-A Sub-nanometer alloy material and preparation method and application thereof 中国科学院上海高等研究院 2022-09-23 CN claimed
US-20220143200-A1 COMPOSITION OF POLYETHYLENE GLYCOL MALEIMIDE DERIVATIVE AND POLYMERIZATION INHIBITOR JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) 2022-05-12 US claimed
CN-110628038-B Covalent triazine organic framework, limited-area metal catalyst, preparation method and application 中国科学院上海高等研究院 2022-03-29 CN claimed
EP-3604480-B1 COMPOSITION OF POLYETHYLENE GLYCOL MALEIMIDE DERIVATIVE AND POLYMERIZATION INHIBITOR JENKEM TECH CO LTD BEIJING (CN) 2022-01-26 EP claimed
CN-108484809-A Olefin polymerization catalyst 中国石油天然气股份有限公司 2018-09-04 CN claimed
CN-108341903-A Olefin polymerization catalyst 中国石油天然气股份有限公司 2018-07-31 CN claimed
CN-104497021-B There is triazole-Tetrafluoroboric acid copper complex of catalysis 4-methoxyphenylboronic acid and preparation method thereof 天津师范大学 2016-10-12 CN claimed
CN-104497019-B Double triazole-cupric perchlorate complex of anthracene nucleus with catalysis 4-methoxyphenylboronic acid and preparation method thereof 天津师范大学 2016-06-29 CN claimed
CN-104447814-B Double triazole-tetrafluoro boric acid copper complex of anthracene nucleus with catalysis 4-methoxyphenylboronic acid and preparation method thereof 天津师范大学 2016-06-29 CN claimed
CN-104530094-B Triazole-cupric perchlorate coordination compound with catalysis 4-methoxyphenylboronic acid and preparation method thereof 天津师范大学 2016-06-08 CN claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
US-4424277-A SULFURIC ACID, DIETHER OF BIPHENOL, COLORIMETRIC ANALYSIS Merck Patent Gesellschaft mit beschra/ nkter Haftung (DE) 1984-01-03 US claimed
EP-0052762-A1 Method and agent for the determination of nitrate ions MERCK PATENT GmbH (DE) 1982-06-02 EP claimed
US-4269977-A Process for the manufacture of 8-oxo-5-thia-1-azabicyclo [4,2,0]oct-2-ene or 3-ene compounds CIBA-GEIGY CORPORATION (US) 1981-05-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220143200-A1 COMPOSITION OF POLYETHYLENE GLYCOL MALEIMIDE DERIVATIVE AND POLYMERIZATION INHIBITOR TFPI, PCNA, CCNI CA1 3621/4885CA2 3802/4885CA7 2778/4885
US-11844842-B2 Composition of polyethylene glycol maleimide derivative and polymerization inhibitor TFPI, PCNA, CCNI CA1 3621/4885CA2 3802/4885CA7 2778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.