SCHEMBL920933

SCHEMBL920933

COc1ccc(-c2ccc(-c3cc(-c4ccc(-c5ccc(OC)cc5)cc4)cc(-c4ccc(-c5ccc(OC)cc5)cc4)c3)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 4/20 0.71
ABCB1 P08183 4/20 0.71
BCR P11274 4/20 0.71
MAPK1 P28482 2/20 0.70
NPC1 O15118 1/20 0.70
TP53 P04637 1/20 0.70
CASP3 P42574 1/20 0.70
RAB9A P51151 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.70
SENP8 Q96LD8 1/20 0.70
SENP7 Q9BQF6 1/20 0.70
SENP6 Q9GZR1 1/20 0.70
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA12 O43570 1/20 0.65
CA14 Q9ULX7 1/20 0.65
ESR2 Q92731 1/20 0.64
HSD17B1 P14061 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3743494 1.00 ABL1 (0.71) ABL1ABCB1BCRMAPK1NPC1
SCHEMBL197522 0.91 CA1 (0.79) ABL1ABCB1BCRMAPK1NPC1
SCHEMBL9151672 0.91 CA1 (0.79) ABL1ABCB1BCRMAPK1NPC1
SCHEMBL6733562 0.91 CA1 (0.79) ABL1ABCB1BCRMAPK1NPC1
SCHEMBL28102062 0.90 ABL1 (0.73) ABL1ABCB1BCRMAPK1NPC1
SCHEMBL19301040 0.90 ABL1 (0.61) ABL1ABCB1BCRMAPK1NPC1
SCHEMBL2274524 0.89 ABL1 (0.79) ABL1ABCB1BCRMAPK1NPC1
SCHEMBL24462151 0.88 ABL1 (0.59) ABL1ABCB1BCRMAPK1NPC1
SCHEMBL15679887 0.88 ABL1 (0.59) ABL1ABCB1BCRMAPK1NPC1
SCHEMBL22229667 0.88 ABL1 (0.59) ABL1ABCB1BCRMAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7871755-B2 Photosensitive composition KABUSHIKI KAISHA TOSHIBA (JP) 2011-01-18 US disclosed
US-7871755-B2 Photosensitive composition KABUSHIKI KAISHA TOSHIBA (JP) 2011-01-18 US disclosed
US-7871755-B2 Photosensitive composition KABUSHIKI KAISHA TOSHIBA (JP) 2011-01-18 US disclosed
US-20090081582-A1 irradiating a predetermined region of photosensitive layer, subjecting the photosensitive layer after baking to development treatment with an alkali aqueous solution to selectively remove the light-exposed part; has a photo-acid generator which generates an acid by the action of actinic radiation KABUSHIKI KAISHA TOSHIBA 2009-03-26 US disclosed
US-20090081582-A1 irradiating a predetermined region of photosensitive layer, subjecting the photosensitive layer after baking to development treatment with an alkali aqueous solution to selectively remove the light-exposed part; has a photo-acid generator which generates an acid by the action of actinic radiation KABUSHIKI KAISHA TOSHIBA 2009-03-26 US disclosed
US-20090081582-A1 irradiating a predetermined region of photosensitive layer, subjecting the photosensitive layer after baking to development treatment with an alkali aqueous solution to selectively remove the light-exposed part; has a photo-acid generator which generates an acid by the action of actinic radiation KABUSHIKI KAISHA TOSHIBA 2009-03-26 US disclosed