Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28444935 | 0.85 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL1974952 | 0.82 | KDM4E (0.60) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL28193649 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL28193691 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL28194136 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL28452660 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL10726878 | 0.77 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPTCYP1A2CYP2C19 | |
| SCHEMBL28459670 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL28194128 | 0.76 | TSHR (0.48) | ALDH1A1HPGDMAPTKDM4ECYP1A2 | |
| SCHEMBL28193672 | 0.76 | TSHR (0.48) | ALDH1A1HPGDMAPTKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619908-A | Green synthesis process of 4, 6-dimethyl-2-oxo-2H-pyran-5-ethyl formate | 无锡小荷智化科技有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-118772100-A | Green technology for synthesizing 4-methyl-6-alkyl-2H-pyran-2-one | 无锡小荷智化科技有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118702662-A | Green technology for synthesizing 4-methyl-2H-pyran-2, 6 (3H) -dione | 无锡小荷智化科技有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118619908-A | Green synthesis process of 4, 6-dimethyl-2-oxo-2H-pyran-5-ethyl formate | 无锡小荷智化科技有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-113717062-A | Compound, polymer, liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, and production method | 捷恩智株式会社 | 2021-11-30 | — | — | CN | disclosed |
| CN-105713553-A | Silicone sealant for aluminum alloy doors/windows | 烟台图文马克化工科技有限公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-105713553-A | Silicone sealant for aluminum alloy doors/windows | 烟台图文马克化工科技有限公司 | 2016-06-29 | — | — | CN | disclosed |
| EP-2513061-A1 | PYRIDONE DERIVATIVES AS NK3 ANTAGONISTS | H. Lundbeck A/S (DK) | 2012-10-24 | — | — | EP | disclosed |
| US-8207347-B2 | Pyridone derivatives as NK3 antagonists | H. LUNDBECK A/S (DK) | 2012-06-26 | — | — | US | disclosed |
| WO-2011072691-A1 | PYRIDONE DERIVATIVES AS NK3 ANTAGONISTS | H. LUNDBECK A/S (DK) | 2011-06-23 | — | — | WO | disclosed |
| US-20110144164-A1 | Pyridone derivatives as NK3 antagonists | H. LUNDBECK A/S (DK) | 2011-06-16 | — | — | US | disclosed |
| US-4486588-A | Cyclohexadiene carboxylate insecticide intermediates | FMC CORPORATION (US) | 1984-12-04 | — | — | US | disclosed |
| US-4375476-A | MITICIDES | FMC CORPORATION (US) | 1983-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144164-A1 | Pyridone derivatives as NK3 antagonists | KCNK3, GRIK3, KCND3 | ALDH1A1 2028/4885HPGD 487/4885MAPT 1976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.