Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970938 | 0.68 | PDE10A (0.38) | PDE10AALDH1A1CDK5CDK5R1 | |
| SCHEMBL942118 | 0.60 | ALDH1A1 (0.39) | PDE10AALDH1A1CDK5CDK5R1 | |
| SCHEMBL16937411 | 0.60 | CYP3A4 (0.50) | ALDH1A1 | |
| SCHEMBL28450674 | 0.60 | MAP4K4 (0.49) | ALDH1A1 | |
| SCHEMBL28216630 | 0.57 | ALDH1A1 (0.37) | PDE10AALDH1A1CDK5CDK5R1 | |
| SCHEMBL28729915 | 0.57 | CHEK1 (0.43) | ALDH1A1CDK5 | |
| Benzidine SCHEMBL9766924 | 0.57 | CYP3A4 (0.65) | ALDH1A1 | |
| SCHEMBL30092397 | 0.57 | PLA2G7 (0.65) | PDE10AALDH1A1 | |
| SCHEMBL31607621 | 0.57 | PLA2G7 (0.65) | PDE10AALDH1A1 | |
| SCHEMBL8848693 | 0.57 | PLA2G7 (0.65) | PDE10AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765894-B2 | Norbornene-type polymers having quaternary ammonium functionality | PROMERUS, LLC (US) | 2014-07-01 | — | — | US | disclosed |
| US-8765893-B2 | Norbornene-type polymers having quaternary ammonium functionality | PROMERUS, LLC (US) | 2014-07-01 | — | — | US | disclosed |
| EP-2510036-A2 | NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY | Promerus LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| US-20110244368-A1 | NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY | PROMERUS LLC (US) | 2011-10-06 | — | — | US | disclosed |
| US-20110143260-A1 | NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY | PROMERUS LLC (US) | 2011-06-16 | — | — | US | disclosed |
| WO-2011072304-A2 | NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY | PROMERUS LLC (US) | 2011-06-16 | — | — | WO | disclosed |