Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 16/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473479 | 0.90 | AGTR1 (0.40) | AGTR1ABCB11GP6LTB4R2AGTR2 | |
| SCHEMBL2692 | 0.88 | AGTR1 (0.44) | AGTR1ABCB11GP6LTB4R2AGTR2 | |
| SCHEMBL2400 | 0.87 | AGTR1 (0.48) | AGTR1ABCB11GP6LTB4R2 | |
| SCHEMBL1975 | 0.87 | AGTR1 (0.48) | AGTR1ABCB11GP6LTB4R2 | |
| SCHEMBL2780 | 0.82 | FFAR1 (0.35) | AGTR1AGTR2PKM | |
| SCHEMBL2529 | 0.79 | AGTR1 (0.53) | AGTR1ABCB11GP6LTB4R2AGTR2 | |
| SCHEMBL7270257 | 0.78 | AGTR1 (0.55) | AGTR1ABCB11GP6LTB4R2 | |
| SCHEMBL7270259 | 0.78 | AGTR1 (0.55) | AGTR1ABCB11GP6LTB4R2 | |
| SCHEMBL2773 | 0.78 | AGTR1 (0.51) | AGTR1ABCB11GP6LTB4R2AGTR2 | |
| SCHEMBL8477037 | 0.78 | AGTR1 (0.51) | AGTR1ABCB11GP6LTB4R2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |