Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2141 | 0.87 | FFAR1 (0.43) | FFAR1AKR1B1KDM5AAGTR1KDM4A | |
| SCHEMBL2779 | 0.86 | AGTR1 (0.42) | FFAR1AKR1B1AGTR1OXTRAVPR1A | |
| SCHEMBL1976 | 0.82 | AGTR1 (0.36) | AGTR1AGTR2PKM | |
| SCHEMBL2438545 | 0.78 | FFAR1 (0.48) | FFAR1AKR1B1OXTRAVPR1APTPN1 | |
| SCHEMBL3133 | 0.78 | PDCD1 (0.43) | FFAR1AKR1B1PTPN1CTSLCTSS | |
| SCHEMBL2700 | 0.78 | AGTR1 (0.47) | FFAR1AKR1B1KDM5AAGTR1KDM4A | |
| SCHEMBL2034 | 0.78 | AGTR1 (0.47) | FFAR1AKR1B1KDM5AAGTR1KDM4A | |
| SCHEMBL7276200 | 0.76 | AGTR1 (0.48) | AGTR1CYP2C9S1PR1 | |
| SCHEMBL2443439 | 0.76 | LTB4R2 (0.44) | FFAR1AKR1B1AGTR1OXTRAVPR1A | |
| SCHEMBL1809623 | 0.75 | AGTR1 (0.54) | FFAR1AKR1B1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |