SCHEMBL1976079

SCHEMBL1976079

O=S(=O)(O)c1ccc(C=Cc2ccc(N=C=S)c(N=C=S)c2S(=O)(=O)O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD1 O60671 1/20 0.42
P2RY6 Q15077 1/20 0.42
APEX1 P27695 1/20 0.41
RAD51 Q06609 4/20 0.36
TDP1 Q9NUW8 3/20 0.36
KDM4E B2RXH2 2/20 0.36
USP2 O75604 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LTA P01374 2/20 0.36
CYP3A4 P08684 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
P2RX3 P56373 2/20 0.36
HSD17B10 Q99714 2/20 0.36
SENP3 Q9H4L4 2/20 0.33
SENP2 Q9HC62 2/20 0.33
SENP1 Q9P0U3 2/20 0.33
SUMO2 P61956 1/20 0.33
SUMO1 P63165 1/20 0.33
SENP7 Q9BQF6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156114 0.81 RAD1 (0.50) RAD1P2RY6APEX1RAD51TDP1
SCHEMBL2834143 0.80 RAD1 (0.51) RAD1P2RY6APEX1RAD51TDP1
SCHEMBL29225411 0.80 P2RY6 (0.53) RAD1P2RY6APEX1RAD51TDP1
SCHEMBL1295716 0.77 RAD1 (0.41) RAD1P2RY6APEX1RAD51TDP1
SCHEMBL9358952 0.76 RAD1 (0.41) RAD1P2RY6APEX1RAD51TDP1
SCHEMBL28624248 0.75 RAD1 (0.42) RAD1P2RY6APEX1RAD51TDP1
SCHEMBL4780292 0.75 RAD1 (0.42) RAD1P2RY6APEX1RAD51TDP1
SCHEMBL28840180 0.74 RAD51 (0.35) RAD51TDP1SENP3SENP2SENP1
Iodide SCHEMBL28771601 0.74 RAD51 (0.35) RAD51TDP1SENP3SENP2SENP1
SCHEMBL2834140 0.71 RAD1 (0.48) RAD1P2RY6APEX1RAD51TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115141789-A Luterion and isolation and culture method thereof 株式会社露太利温 2022-10-04 CN disclosed
CN-114040919-A Fluorescence labeling nucleic acid and synthetic method thereof 南京金斯瑞生物科技有限公司 2022-02-11 CN disclosed
CN-113646444-A Method for detecting legionella 奎斯特诊断投资有限责任公司 2021-11-12 CN disclosed
CN-108700519-B Methods and compositions for fluorescence detection 生物辐射实验室股份有限公司 2021-07-30 CN disclosed
CN-112870163-A Hybrid, composition containing the hybrid, preparation method and use thereof 安杰瑞姆生物科学公司 2021-06-01 CN disclosed
US-9114151-B2 Method for modulating or controlling sodium channel current by reactive oxygen species (ROS) originating from mitochondria THE UNITED STATES OF AMERICA DEPT. OF VETERANS AFFAIRS (US) 2015-08-25 US disclosed
US-20110144192-A1 Method for modulating or controlling sodium channel current by reactive oxygen species (ROS) originating from mitochondria U.S. DEPARTMENT OF VETERANS AFFAIRS (US) 2011-06-16 US disclosed