Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD1 | O60671 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | LTA | P01374 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.34 |
| ▸ | SENP3 | Q9H4L4 | 5/20 | 0.33 |
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 5/20 | 0.33 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.33 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624248 | 0.76 | RAD1 (0.42) | RAD1P2RY6APEX1TDP1ALDH1A1 | |
| SCHEMBL1976079 | 0.76 | RAD1 (0.42) | RAD1P2RY6APEX1TDP1ALDH1A1 | |
| SCHEMBL1295716 | 0.75 | RAD1 (0.41) | RAD1P2RY6APEX1TDP1ALDH1A1 | |
| SCHEMBL4780292 | 0.74 | RAD1 (0.42) | RAD1P2RY6APEX1TDP1ALDH1A1 | |
| SCHEMBL2834140 | 0.73 | RAD1 (0.48) | RAD1P2RY6APEX1TDP1ALDH1A1 | |
| SCHEMBL156112 | 0.72 | RAD1 (0.47) | RAD1P2RY6APEX1TDP1ALDH1A1 | |
| SCHEMBL29225411 | 0.71 | P2RY6 (0.53) | RAD1P2RY6APEX1TDP1ALDH1A1 | |
| SCHEMBL156114 | 0.71 | RAD1 (0.50) | RAD1P2RY6APEX1TDP1ALDH1A1 | |
| SCHEMBL2834143 | 0.69 | RAD1 (0.51) | RAD1P2RY6APEX1TDP1ALDH1A1 | |
| SCHEMBL7521581 | 0.68 | TSHR (0.56) | TDP1ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626945-A1 | SULFONIC ACID DERIVATIVES IN THE TREATMENT OF VIRAL DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993016992-A1 | SULFONIC ACID DERIVATIVES IN THE TREATMENT OF VIRAL DISEASES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-02 | — | — | WO | disclosed |