Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD1 | O60671 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | LTA | P01374 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780292 | 0.90 | RAD1 (0.42) | RAD1P2RY6APEX1ALDH1A1KDM4E | |
| SCHEMBL1295716 | 0.89 | RAD1 (0.41) | RAD1P2RY6APEX1ALDH1A1KDM4E | |
| SCHEMBL9358952 | 0.76 | RAD1 (0.41) | RAD1P2RY6APEX1ALDH1A1KDM4E | |
| SCHEMBL1976079 | 0.75 | RAD1 (0.42) | RAD1P2RY6APEX1ALDH1A1KDM4E | |
| SCHEMBL28378328 | 0.75 | PTPN1 (0.34) | RAD51TRPA1HTR2AHTR2CKCNH2 | |
| SCHEMBL2834143 | 0.72 | RAD1 (0.51) | RAD1P2RY6APEX1ALDH1A1KDM4E | |
| SCHEMBL156114 | 0.72 | RAD1 (0.50) | RAD1P2RY6APEX1ALDH1A1KDM4E | |
| SCHEMBL28420132 | 0.71 | ALDH1A1 (0.42) | ALDH1A1CYP3A4HPGDHSD17B10TDP1 | |
| SCHEMBL2834140 | 0.71 | RAD1 (0.48) | RAD1P2RY6APEX1ALDH1A1KDM4E | |
| SCHEMBL18528944 | 0.70 | NFE2L2 (0.46) | ALDH1A1CYP3A4HPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115354076-A | Detection of Gene fusions by Intragenic Differential Expression (IDE) Using average cycle threshold | 奎斯特诊断投资股份有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-110268247-B | Measurement of protein-protein interactions at the Single molecule level | 生物辐射实验室股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-108351351-B | Assays using avidin and biotin | 生物辐射实验室股份有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-113164595-A | Anti-human CD45RC antibodies and uses thereof | 法国国家健康和医学研究院 | 2021-07-23 | — | — | CN | disclosed |