SCHEMBL197633

SCHEMBL197633

O=C(c1ccccc1)c1ccc(-c2ccc(C(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.82
MEN1 O00255 3/20 0.82
KMT2A Q03164 3/20 0.82
MAPT P10636 2/20 0.82
LMNA P02545 1/20 0.82
ALDH1A1 P00352 1/20 0.78
SRD5A2 P31213 2/20 0.71
CA12 O43570 1/20 0.67
CA1 P00915 1/20 0.67
CA2 P00918 1/20 0.67
CA9 Q16790 1/20 0.67
CA14 Q9ULX7 1/20 0.67
ATM Q13315 2/20 0.64
TDP1 Q9NUW8 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
CDC25B P30305 1/20 0.61
POLB P06746 1/20 0.61
MAPK1 P28482 1/20 0.61
NPC1 O15118 3/20 0.60
CTDSP1 Q9GZU7 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13019488 1.00 RAB9A (0.82) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL29143580 0.97 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
Benzophenone SCHEMBL28231198 0.97 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
Benzophenone SCHEMBL15567912 0.97 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL41657 0.97 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL28246134 0.97 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
Benzene SCHEMBL28384085 0.97 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL13534566 0.97 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL232724 0.94 RAB9A (0.74) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL27556386 0.93 RAB9A (0.72) RAB9AMEN1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4970284-A Polyaryletherketones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-11-13 US claimed
EP-0323076-A2 Polyaryletherketones VICTREX MANUFACTURING LIMITED (GB) 1989-07-05 EP claimed
US-9982105-B2 Surface modification method and surface-modified elastic body SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2018-05-29 US disclosed
US-9453103-B2 Method for producing aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-09-27 US disclosed
US-9453103-B2 Method for producing aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-09-27 US disclosed
US-9238665-B2 Method for producing aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-01-19 US disclosed
US-9238665-B2 Method for producing aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-01-19 US disclosed
US-20150322199-A1 METHOD FOR PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-12 US disclosed
US-20150322199-A1 METHOD FOR PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-12 US disclosed
US-20150322101-A1 METHOD FOR PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-12 US disclosed
US-20150322101-A1 METHOD FOR PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-12 US disclosed
US-4767837-A Method for preparing poly(aryl ether ketones) RAYCHEM CORPORATION (US) 1988-08-30 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4205016-A Multifunctional lithium containing initiator THE DOW CHEMICAL COMPANY (US) 1980-05-27 US disclosed
US-4201729-A CONTAINING BUTADIENE AND/OR ISOPRENE UNITS THE DOW CHEMICAL COMPANY (US) 1980-05-06 US disclosed
US-4200718-A Multifunctional lithium containing initiator THE DOW CHEMICAL COMPANY (US) 1980-04-29 US disclosed
US-4196153-A POLYMERIZATION CATALYSTS THE DOW CHEMICAL COMPANY (US) 1980-04-01 US disclosed
US-4182818-A POLYMERIZATION OF VINYL COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1980-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150322199-A1 METHOD FOR PRODUCING AROMATIC COMPOUND PAH, DDC, DDT RAB9A 1557/4885MEN1 110/4885KMT2A 1729/4885
US-20150322101-A1 METHOD FOR PRODUCING AROMATIC COMPOUND PAH, DDC, PHOSPHO1 RAB9A 1676/4885MEN1 105/4885KMT2A 1662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.