Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30882585 | 0.84 | PDK2 (0.48) | MAPTPDK2SMN1; SMN2L3MBTL1 | |
| SCHEMBL30882453 | 0.84 | ALDH1A1 (0.47) | MAPTHPGDALDH1A1TSHRPDK2 | |
| SCHEMBL15131513 | 0.82 | PDK2 (0.44) | MAPTPDK2SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL13107406 | 0.79 | PDK2 (0.48) | MAPTPDK2SMN1; SMN2HTTMEN1 | |
| SCHEMBL14692626 | 0.78 | GSK3B (0.50) | GSK3BPDK2 | |
| SCHEMBL26120236 | 0.77 | PDK2 (0.48) | MAPTHPGDALDH1A1TSHRPDK2 | |
| SCHEMBL18012811 | 0.77 | ATM (0.44) | MAPTHPGDALDH1A1TSHRATM | |
| SCHEMBL14733206 | 0.77 | PDK2 (0.39) | MAPTGSK3BPDK2RAB9ANPC1 | |
| SCHEMBL19978302 | 0.76 | KMT2A (0.40) | MAPTHPGDALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL26573486 | 0.76 | PDK2 (0.49) | ALDH1A1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180009790-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF HCV INHIBITOR | VETUKURI PRASAD RAJU VNKV (IN) | 2018-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180009790-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF HCV INHIBITOR | GOT1, EIF2AK2, UGT1A1 | MAPT 3443/4885HPGD 2409/4885ALDH1A1 1412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.