SCHEMBL19765367

SCHEMBL19765367

Cc1cc(-c2cccc3c2Oc2ccccc2S3)c(C)cc1-c1cc(C)c(-c2cccc3c2Oc2ccccc2S3)cc1C

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.50
PRKDC P78527 1/20 0.45
ADK P55263 1/20 0.35
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALOX5 P09917 1/20 0.30
MYC P01106 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4262266 0.82 ATM (0.46) ATMPRKDCADKMEN1KMT2A
SCHEMBL2662938 0.81 ATM (0.46) ATMPRKDCADKMEN1KMT2A
SCHEMBL8302432 0.78 ATM (0.50) ATMPRKDCADKAHR
SCHEMBL19765344 0.78 AHR (0.47) ATMMYCAHR
SCHEMBL19765335 0.77 ATM (0.44) ATMPRKDCADK
SCHEMBL12679743 0.76 ATM (0.46) ATMPRKDCADK
SCHEMBL12489850 0.76 PRKDC (0.47) ATMPRKDCADK
SCHEMBL12487451 0.75 ATM (0.45) ATMPRKDCADK
SCHEMBL12490334 0.74 ATM (0.44) ATMPRKDCADKMEN1KMT2A
SCHEMBL12488705 0.74 ATM (0.44) ATMPRKDCADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180013075-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180013075-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ANKK1, EYA2, KCNN2 ATM 2371/4885PRKDC 1490/4885ADK 1921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.