Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18176151 | 0.99 | THRB (0.45) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL26219726 | 0.94 | THRB (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL11919878 | 0.94 | TSHR (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL19239961 | 0.94 | TSHR (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL17069794 | 0.94 | TSHR (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2367991 | 0.93 | THRB (0.51) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL25602131 | 0.92 | TSHR (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2367838 | 0.92 | TSHR (0.51) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL9764030 | 0.90 | TSHR (0.46) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL10115291 | 0.90 | TSHR (0.46) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820850-B2 | Polymer compositions containing grafted polymeric networks and processes for their preparation and use | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20180100039-A1 | TRI-BLOCK PREPOLYMERS AND THEIR USE IN SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE, INC. | 2018-04-12 | — | — | US | disclosed |
| US-20180037690-A1 | POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE | JOHNSON & JOHNSON VISION CARE, INC. | 2018-02-08 | — | — | US | disclosed |
| US-20180011222-A1 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE, INC. | 2018-01-11 | — | — | US | disclosed |
| US-20180011223-A1 | SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF | JOHNSON & JOHNSON VISION CARE, INC. | 2018-01-11 | — | — | US | disclosed |