Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18176151 | 0.96 | THRB (0.45) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL19765645 | 0.94 | THRB (0.46) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2367366 | 0.92 | THRB (0.54) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL64810 | 0.92 | TSHR (0.55) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL26561519 | 0.90 | TSHR (0.53) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL12755984 | 0.90 | THRB (0.45) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL14130481 | 0.89 | TSHR (0.56) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL17069794 | 0.87 | TSHR (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL17059112 | 0.87 | TSHR (0.50) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL17718723 | 0.87 | TSHR (0.50) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11828913-B2 | Silicone hydrogels comprising polyamides | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11829008-B2 | Increased stiffness center optic in soft contact lenses for astigmatism correction | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11754754-B2 | Silicone hydrogels comprising N-alkyl methacrylamides and contact lenses made thereof | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-09-12 | — | — | US | disclosed |