Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25697671 | 1.00 | MEN1 (0.48) | MEN1KMT2ASIRT1PTGS1PTGS2 | |
| SCHEMBL27237069 | 0.82 | CDK4 (0.46) | MEN1KMT2ASIRT1PTGS1PTGS2 | |
| SCHEMBL27237059 | 0.81 | NPC1 (0.46) | MEN1KMT2ASIRT1PTGS1PTGS2 | |
| SCHEMBL25697678 | 0.80 | P2RY2 (0.40) | MEN1KMT2ANPC1PKM | |
| SCHEMBL25697668 | 0.80 | F12 (0.41) | — | |
| SCHEMBL27237056 | 0.78 | TK1 (0.50) | MEN1KMT2ASIRT1PTGS1NPC1 | |
| SCHEMBL25697669 | 0.76 | P2RY2 (0.42) | — | |
| SCHEMBL25824045 | 0.70 | P2RY2 (0.48) | — | |
| SCHEMBL19834966 | 0.69 | TK2 (0.42) | — | |
| SCHEMBL19834968 | 0.68 | TK2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180016581-A1 | NUCLEIC ACID COMPOUNDS FOR BINDING GROWTH DIFFERENTIATION FACTOR 8 | SOMALOGIC, INC. (US) | 2018-01-18 | — | — | US | disclosed |