Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HINT1 | P49773 | 1/20 | 0.44 |
| ▸ | PYGM | P11217 | 3/20 | 0.43 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.43 |
| ▸ | TK2 | O00142 | 2/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824050 | 0.85 | PYGM (0.50) | P2RY2PYGMDNPH1TK2P2RY6 | |
| SCHEMBL25824044 | 0.85 | TK2 (0.42) | P2RY2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10101281 | 0.82 | TK2 (0.53) | KDM4EALDH1A1PYGMTK2 | |
| SCHEMBL10104844 | 0.82 | TK2 (0.53) | KDM4EALDH1A1PYGMTK2 | |
| SCHEMBL29163657 | 0.82 | TK2 (0.53) | KDM4EALDH1A1PYGMTK2 | |
| SCHEMBL23215178 | 0.81 | TYMP (0.55) | P2RY2HINT1DNPH1P2RY6 | |
| SCHEMBL24420198 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL25697669 | 0.78 | P2RY2 (0.42) | P2RY2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL19768685 | 0.78 | P2RY2 (0.42) | P2RY2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27093309 | 0.78 | TK2 (0.48) | P2RY2PYGMTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |