SCHEMBL19769825

SCHEMBL19769825

c1ccc(-c2ccc(-c3cc(-c4ccc(-c5ccccc5)cc4)nc(-n4c5ccccc5c5cc6c(cc54)c4ccccc4n6-c4ccccc4)n3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.50
KDM4E B2RXH2 3/20 0.50
ATM Q13315 1/20 0.50
MAPT P10636 6/20 0.38
MAPK1 P28482 3/20 0.38
HTT P42858 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
DHODH Q02127 1/20 0.38
KMT2A Q03164 7/20 0.37
IL1R1 P14778 1/20 0.37
MEN1 O00255 6/20 0.37
ALDH1A1 P00352 4/20 0.37
HPGD P15428 3/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NTSR1 P30989 1/20 0.36
HDAC4 P56524 1/20 0.36
ACHE P22303 1/20 0.36
PTGER4 P35408 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19769826 1.00 L3MBTL1 (0.50) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL18708377 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL257173 0.97 L3MBTL1 (0.53) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL19769733 0.96 L3MBTL1 (0.49) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL19769708 0.96 L3MBTL1 (0.49) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL19769827 0.95 KDM4E (0.45) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL8818131 0.95 L3MBTL1 (0.47) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL17548780 0.94 L3MBTL1 (0.50) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL25118748 0.93 L3MBTL1 (0.42) L3MBTL1KDM4EATMMAPTMAPK1
SCHEMBL19769824 0.93 KDM4E (0.46) L3MBTL1KDM4EATMMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME TORAY INDUSTRIES, INC. (JP) 2021-05-20 US disclosed
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device SAMSUNG SDI CO., LTD. (KR) 2019-12-10 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 L3MBTL1 4794/4885KDM4E 4452/4885ATM 4365/4885
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME CBR3, INTS9, CBR1 L3MBTL1 208/4885KDM4E 1196/4885ATM 2844/4885
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device OXER1, OR10J3, OR51E2 L3MBTL1 4812/4885KDM4E 4531/4885ATM 4381/4885
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OR10J3, OR51E2 L3MBTL1 4812/4885KDM4E 4531/4885ATM 4381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.