SCHEMBL17548780

SCHEMBL17548780

c1ccc(-c2cc(-c3ccccc3)nc(-n3c4ccccc4c4cc5c(cc43)c3cc4c6ccccc6n(-c6nc(-c7ccccc7)cc(-c7ccccc7)n6)c4cc3n5-c3ccccc3)n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.50
KDM4E B2RXH2 4/20 0.50
ATM Q13315 2/20 0.50
KMT2A Q03164 6/20 0.37
MAPT P10636 6/20 0.37
MAPK1 P28482 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
IL1R1 P14778 1/20 0.37
MEN1 O00255 5/20 0.37
ALDH1A1 P00352 3/20 0.37
HPGD P15428 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
HTT P42858 3/20 0.36
ACHE P22303 1/20 0.36
AGTR1 P30556 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10018652 0.99 L3MBTL1 (0.51) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL257173 0.97 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL19769733 0.96 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL19769708 0.96 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL19769826 0.94 L3MBTL1 (0.50) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL19769825 0.94 L3MBTL1 (0.50) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL8817653 0.93 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL17809305 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL17279647 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL17809306 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381574-B2 Compound for organic electronic element, organic electrical element using compound, and electronic device comprising same DUK SAN NEOLUX CO., LTD. (KR) 2019-08-13 US disclosed
US-20190103561-A1 Compound For Organic Electronic Element, Organic Electrical Element Using Compound, And Electronic Device Comprising Same DUK SAN NEOLUX CO., LTD (KR) 2019-04-04 US disclosed
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD (KR) 2017-09-07 US disclosed
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME DUK SAN NEOLUX CO., LTD (KR) 2017-09-07 US disclosed
WO-2016032150-A2 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170256719-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRICAL ELEMENT USING COMPOUND, AND ELECTRONIC DEVICE COMPRISING SAME ORAI2, VDAC2, PIEZO1 L3MBTL1 783/4885KDM4E 594/4885ATM 2903/4885
US-20190103561-A1 Compound For Organic Electronic Element, Organic Electrical Element Using Compound, And Electronic Device Comprising Same ORAI2, VDAC2, PIEZO1 L3MBTL1 783/4885KDM4E 594/4885ATM 2903/4885
US-10381574-B2 Compound for organic electronic element, organic electrical element using compound, and electronic device comprising same ORAI2, VDAC2, PIEZO1 L3MBTL1 783/4885KDM4E 594/4885ATM 2903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.