SCHEMBL19769853

SCHEMBL19769853

c1ccc(-c2ccc(-c3nc(-n4c5ccccc5c5cc6c(cc54)c4ccccc4n6-c4ccccc4)nc4ccccc34)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
HPGD P15428 3/20 0.49
MAPT P10636 3/20 0.49
NPSR1 Q6W5P4 1/20 0.49
L3MBTL1 Q9Y468 4/20 0.47
ATM Q13315 3/20 0.46
LMNA P02545 1/20 0.46
MAPK1 P28482 2/20 0.41
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NUDT1 P36639 3/20 0.40
ADORA2A P29274 2/20 0.40
HTT P42858 1/20 0.39
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
HSP90AA1 P07900 1/20 0.38
GAA P10253 1/20 0.38
IL1R1 P14778 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18593804 0.97 ALDH1A1 (0.51) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL18505348 0.96 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL8819293 0.95 KDM4E (0.47) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL23072352 0.94 ALDH1A1 (0.46) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL15583014 0.94 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL22479831 0.94 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL16475779 0.94 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL21578695 0.94 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL16475838 0.94 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1
SCHEMBL15638499 0.94 KDM4E (0.48) KDM4EALDH1A1HPGDMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4231804-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-08-23 EP disclosed
US-20220399517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-15 US disclosed
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME TORAY INDUSTRIES, INC. (JP) 2021-05-20 US disclosed
WO-2021034017-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-25 WO disclosed
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device SAMSUNG SDI CO., LTD. (KR) 2019-12-10 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220399517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSGEP KDM4E 2859/4885ALDH1A1 1043/4885HPGD 1146/4885
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 KDM4E 4452/4885ALDH1A1 158/4885HPGD 1323/4885
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME CBR3, INTS9, CBR1 KDM4E 1196/4885ALDH1A1 214/4885HPGD 4631/4885
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device OXER1, OR10J3, OR51E2 KDM4E 4531/4885ALDH1A1 156/4885HPGD 986/4885
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OR10J3, OR51E2 KDM4E 4531/4885ALDH1A1 156/4885HPGD 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.