SCHEMBL19769858

SCHEMBL19769858

c1ccc(-c2cc(-c3cccc4c3oc3ccccc34)nc(-n3c4ccccc4c4ccc5c(c6ccccc6n5-c5ccccc5)c43)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.34
ATM Q13315 2/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PRKDC P78527 3/20 0.31
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
GGPS1 O95749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19769863 0.98 ALOX5 (0.35) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL16810920 0.96 ALOX5 (0.34) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL16811005 0.95 ALOX5 (0.35) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL12691547 0.94 ALOX5 (0.38) ALOX5ATMPRKDCPIK3CDPIK3CB
SCHEMBL16451997 0.93 ALOX5 (0.34) ALOX5PRKDC
SCHEMBL16811088 0.92 ALOX5 (0.32) ALOX5
SCHEMBL16810942 0.92 ALOX5 (0.34) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL19769755 0.92 ALOX5 (0.37) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL19342717 0.92 ALOX5 (0.37) ALOX5ATMKDM4EL3MBTL1PRKDC
SCHEMBL16451996 0.91 ALOX5 (0.32) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device SAMSUNG SDI CO., LTD. (KR) 2019-12-10 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 ALOX5 346/4885ATM 4365/4885KDM4E 4452/4885
US-10505126-B2 Composition for organic optoelectric device and organic optoelectric device and display device OXER1, OR10J3, OR51E2 ALOX5 365/4885ATM 4381/4885KDM4E 4531/4885
US-20180026204-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OR10J3, OR51E2 ALOX5 365/4885ATM 4381/4885KDM4E 4531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.