SCHEMBL16811005

SCHEMBL16811005

c1ccc(-c2ccc(-c3cc(-c4cccc5c4oc4ccccc45)nc(-n4c5ccccc5c5c4ccc4c6ccccc6n(-c6ccccc6)c45)n3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.35
PRKDC P78527 2/20 0.32
PIK3CD O00329 1/20 0.30
PIK3CB P42338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16810920 0.98 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL19769863 0.96 ALOX5 (0.35) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL16811088 0.96 ALOX5 (0.32) ALOX5
SCHEMBL19769858 0.95 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL16811036 0.92 ALOX5 (0.35) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL19769759 0.92 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL16451997 0.91 ALOX5 (0.34) ALOX5PRKDC
SCHEMBL16452048 0.91 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL16810942 0.90 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL16810990 0.90 ALOX5 (0.39) ALOX5PRKDCPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210226134-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2021-07-22 US disclosed
US-20210119148-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2021-04-22 US disclosed
US-10985329-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-04-20 US disclosed
US-20190074451-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2019-03-07 US disclosed
US-20150171340-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-06-18 US disclosed
US-20150171340-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210226134-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNE2, CRY2 ALOX5 1964/4885PRKDC 4795/4885PIK3CD 4124/4885
US-10985329-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CCNE2, CRY2 ALOX5 1964/4885PRKDC 4795/4885PIK3CD 4124/4885
US-20210119148-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNE2, CRY2 ALOX5 1964/4885PRKDC 4795/4885PIK3CD 4124/4885
US-20190074451-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNE2, CRY2 ALOX5 1964/4885PRKDC 4795/4885PIK3CD 4124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.