Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.86 |
| ▸ | CYCS | P99999 | 4/20 | 0.83 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.47 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.47 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9976608 | 1.00 | TOP1 (0.86) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL709532 | 0.93 | TOP1 (1.00) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL29354037 | 0.93 | TOP1 (1.00) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL30928977 | 0.91 | TOP1 (0.97) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL31463636 | 0.91 | TOP1 (0.97) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL31439152 | 0.91 | TOP1 (0.97) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL17183606 | 0.91 | TOP1 (0.97) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL19640853 | 0.91 | CYCS (1.00) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL3047596 | 0.91 | TOP1 (0.97) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL12842181 | 0.91 | CYCS (0.97) | TOP1CYCSABCG2ENPP2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9205420-B2 | Nanostructures, systems, and methods for photocatalysis | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-12-08 | — | — | US | disclosed |
| WO-2013006427-A1 | METHODS AND SYSTEMS USEFUL FOR SOLAR ENERGY STORAGE | SUN CATALYTIX CORPORATION (US) | 2013-01-10 | — | — | WO | disclosed |
| EP-1809332-B1 | COMPOSITIONS FOR MULTI-STEP DELIVERY OF HOT-SPOTS RADIATION TO CANCER CELLS | ONCOLOGIC INC (US) | 2011-12-14 | — | — | EP | disclosed |
| US-20110142756-A1 | Method And Composition For The Treatment Of Cancer By The Enzymatic Conversion Of Soluble Radioactive Toxic Precipitates In The Cancer | Rose, David S. (US) | 2011-06-16 | — | — | US | disclosed |
| US-7922891-B2 | Methods for detection and quantification of analytes | ARIZONA BOARD OF REGENTS (US) | 2011-04-12 | — | — | US | disclosed |
| US-7922891-B2 | Methods for detection and quantification of analytes | ARIZONA BOARD OF REGENTS (US) | 2011-04-12 | — | — | US | disclosed |
| US-7807136-B2 | Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic precipitates in the cancer | Rose, David S. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20100062006-A9 | Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic precipitates in the cancer | MAYERS GEORGE L | 2010-03-11 | — | — | US | disclosed |
| US-7615221-B2 | Compositions and methods for treating cancer | ONCOLOGIC, INC. (US) | 2009-11-10 | — | — | US | disclosed |
| US-20070184309-A1 | Methods for use of a photobiofuel cell in production of hydrogen and other materials | GUST JR JOHN D | 2007-08-09 | — | — | US | disclosed |
| US-20070184309-A1 | Methods for use of a photobiofuel cell in production of hydrogen and other materials | GUST JR JOHN D | 2007-08-09 | — | — | US | disclosed |
| US-20070175770-A1 | Methods for detection and quantification of analytes | ARIZONA BOARD OF REGENTS | 2007-08-02 | — | — | US | disclosed |
| US-20070175770-A1 | Methods for detection and quantification of analytes | ARIZONA BOARD OF REGENTS | 2007-08-02 | — | — | US | disclosed |
| EP-1809332-A2 | COMPOSITIONS FOR MULTI-STEP DELIVERY OF HOT-SPOTS RADIATION TO CANCER CELLS | Oncologic, Inc. (US) | 2007-07-25 | — | — | EP | disclosed |
| US-20060018908-A1 | Compositions and methods for treating cancer | ROSE, DAVID STUART | 2006-01-26 | — | — | US | disclosed |
| WO-2006010165-A2 | COMPOSITIONS FOR MULTI-STEP DELIVERY OF HOT-SPOTS RADIATION TO CANCER CELLS | ONCOLOGIC, INC. (US) | 2006-01-26 | — | — | WO | disclosed |
| US-20050058652-A1 | Method and composition for the treatment of cancer by the enzymatic conversion of soluble radioactive toxic precipitates in the cancer | ROSE, DAVID STUART | 2005-03-17 | — | — | US | disclosed |
| WO-1994009826-A2 | DRUG DELIVERY SYSTEMS, CHARACTERISED BY A PHOTOLABILE LINKAGE | MEDIPRO SCIENCES LIMITED (CA) | 1994-05-11 | — | — | WO | disclosed |
| US-5286474-A | Use of carotenoporphyrins as tumor localizing agents for diagnosis | ARIZONA BOARD OF REGENTS, A BODY CORPORATE, ACTING FOR AND ON BEHALF THE ARIZONA STATE UNIVERSITY (US) | 1994-02-15 | — | — | US | disclosed |