Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.86 |
| ▸ | CYCS | P99999 | 4/20 | 0.83 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.47 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.47 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1977052 | 1.00 | TOP1 (0.86) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL709532 | 0.93 | TOP1 (1.00) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL29354037 | 0.93 | TOP1 (1.00) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL30928977 | 0.91 | TOP1 (0.97) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL31463636 | 0.91 | TOP1 (0.97) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL31439152 | 0.91 | TOP1 (0.97) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL17183606 | 0.91 | TOP1 (0.97) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL19640853 | 0.91 | CYCS (1.00) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL3047596 | 0.91 | TOP1 (0.97) | TOP1CYCSABCG2ENPP2TERT | |
| SCHEMBL12842181 | 0.91 | CYCS (0.97) | TOP1CYCSABCG2ENPP2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150118313-A1 | ENHANCED FOLIC ACID FLUORESCENT MATERIAL, MULTIFLUORESCENT POROUS COMPOSITIONS OF MATTER AND POTENTIAL APPLICATIONS THEREOF | NANOLOGICA AB (SE) | 2015-04-30 | — | — | US | disclosed |
| US-20130058987-A1 | ENHANCED FOLIC ACID FLUORESCENT MATERIAL, MULTIFLUORESCENT POROUS COMPOSITIONS OF MATTER AND POTENTIAL APPLICATIONS THEREOF | NANOLOGICA AB (SE) | 2013-03-07 | — | — | US | disclosed |
| US-20120157824-A1 | MRI AND OPTICAL ASSAYS FOR PROTEASES | NANOSCALE CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120157824-A1 | MRI AND OPTICAL ASSAYS FOR PROTEASES | NANOSCALE CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150118313-A1 | ENHANCED FOLIC ACID FLUORESCENT MATERIAL, MULTIFLUORESCENT POROUS COMPOSITIONS OF MATTER AND POTENTIAL APPLICATIONS THEREOF | FOLR1, FOLR2, SLC19A1 | TOP1 3035/4885CYCS 2941/4885ABCG2 35/4885 |
| US-20120157824-A1 | MRI AND OPTICAL ASSAYS FOR PROTEASES | PREP, HPN, ADAM9 | TOP1 3616/4885CYCS 4383/4885ABCG2 4124/4885 |
| US-20130058987-A1 | ENHANCED FOLIC ACID FLUORESCENT MATERIAL, MULTIFLUORESCENT POROUS COMPOSITIONS OF MATTER AND POTENTIAL APPLICATIONS THEREOF | FOLR1, FOLR2, SLC19A1 | TOP1 3035/4885CYCS 2941/4885ABCG2 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.