Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16392371 | 1.00 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2HCRTR1PPIA | |
| SCHEMBL16585564 | 0.89 | HCRTR1 (0.47) | TAS1R3TAS1R1TAS1R2HCRTR1PPIA | |
| SCHEMBL16585567 | 0.89 | HCRTR1 (0.47) | TAS1R3TAS1R1TAS1R2HCRTR1PPIA | |
| SCHEMBL16585565 | 0.89 | HCRTR1 (0.47) | TAS1R3TAS1R1TAS1R2HCRTR1PPIA | |
| SCHEMBL17598751 | 0.87 | HCRTR1 (0.52) | TAS1R3TAS1R1TAS1R2HCRTR1PPIA | |
| SCHEMBL17799693 | 0.85 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2HCRTR1PPIA | |
| SCHEMBL16451641 | 0.80 | HCRTR1 (0.45) | TAS1R3TAS1R1TAS1R2HCRTR1PPIA | |
| SCHEMBL15295033 | 0.80 | HCRTR1 (0.45) | TAS1R3TAS1R1TAS1R2HCRTR1PPIA | |
| SCHEMBL16451640 | 0.80 | HCRTR1 (0.45) | TAS1R3TAS1R1TAS1R2HCRTR1PPIA | |
| SCHEMBL15295032 | 0.80 | HCRTR1 (0.45) | TAS1R3TAS1R1TAS1R2HCRTR1PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9867371-B2 | 4-membered ring carboxamides used as nematicides | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-16 | — | — | US | disclosed |