Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 5/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.47 |
| ▸ | PPIA | P62937 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16585567 | 1.00 | HCRTR1 (0.47) | HCRTR1TAS1R3TAS1R1TAS1R2PPIA | |
| SCHEMBL16585565 | 1.00 | HCRTR1 (0.47) | HCRTR1TAS1R3TAS1R1TAS1R2PPIA | |
| SCHEMBL19771732 | 0.89 | TAS1R3 (0.51) | HCRTR1TAS1R3TAS1R1TAS1R2PPIA | |
| SCHEMBL16392371 | 0.89 | TAS1R3 (0.51) | HCRTR1TAS1R3TAS1R1TAS1R2PPIA | |
| SCHEMBL17598751 | 0.87 | HCRTR1 (0.52) | HCRTR1TAS1R3TAS1R1TAS1R2PPIA | |
| SCHEMBL17799693 | 0.83 | TAS1R3 (0.47) | HCRTR1TAS1R3TAS1R1TAS1R2PPIA | |
| SCHEMBL17598752 | 0.79 | HCRTR1 (0.51) | HCRTR1TAS1R3TAS1R1TAS1R2PPIA | |
| SCHEMBL15295032 | 0.78 | HCRTR1 (0.45) | HCRTR1TAS1R3TAS1R1TAS1R2PPIA | |
| SCHEMBL16451640 | 0.78 | HCRTR1 (0.45) | HCRTR1TAS1R3TAS1R1TAS1R2PPIA | |
| SCHEMBL16451641 | 0.78 | HCRTR1 (0.45) | HCRTR1TAS1R3TAS1R1TAS1R2PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015040141-A1 | CYCLOBUTYLCARBOXAMIDES AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-03-26 | — | — | WO | disclosed |