Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 known ✓ | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 known ✓ | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL1977255 | 0.94 | CA4 (0.42) | CA4CA2CA1TP53SLC22A16 | |
| L-Lactic Acid SCHEMBL7120021 | 0.94 | CA4 (0.48) | CA4CA2CA1TP53SLC22A16 | |
| L-Lactic Acid SCHEMBL15008848 | 0.94 | CA4 (0.42) | CA4CA2CA1TP53SLC22A16 | |
| L-Lactic Acid SCHEMBL15441340 | 0.94 | CA4 (0.42) | CA4CA2CA1TP53SLC22A16 | |
| L-Lactic Acid SCHEMBL7120010 | 0.94 | CA4 (0.42) | CA4CA2CA1TP53SLC22A16 | |
| L-Lactic Acid SCHEMBL29427623 | 0.94 | CA2 (0.48) | CA4CA2CA1TP53SLC22A16 | |
| L-Lactic Acid SCHEMBL15441342 | 0.81 | TP53 (0.43) | CA4CA2CA1TP53CYP3A4 | |
| L-Lactic Acid SCHEMBL16585424 | 0.80 | TSHR (0.42) | CA4CA2CA1TP53CYP3A4 | |
| L-Lactic Acid SCHEMBL16585426 | 0.80 | TSHR (0.42) | CA4CA2CA1TP53CYP3A4 | |
| L-Lactic Acid SCHEMBL28219862 | 0.80 | TSHR (0.42) | CA4CA2CA1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 536 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329478-B2 | Aldehydes as a catalyst for an oxidative breaker | HALLIBURTON ENERGY SERVICES, INC. (US) | 2019-06-25 | — | — | US | claimed |
| US-20170335172-A1 | ALDEHYDES AS A CATALYST FOR AN OXIDATIVE BREAKER | HALLIBURTON ENERGY SERVICES, INC. | 2017-11-23 | — | — | US | claimed |
| US-9732265-B2 | Ampholyte polymers and methods of treating subterranean formations with the same | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-08-15 | — | — | US | claimed |
| US-20170114272-A1 | Scale Inhibitor and Methods of Using Scale Inhibitors | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-04-27 | — | — | US | claimed |
| US-9512349-B2 | Solid-supported crosslinker for treatment of a subterranean formation | HALLIBURTON ENERGY SERVICES, INC. (US) | 2016-12-06 | — | — | US | claimed |
| WO-2016099502-A1 | ALDEHYDES AS A CATALYST FOR AN OXIDATIVE BREAKER | HALLIBURTON ENERGY SERVICES, INC. (US) | 2016-06-23 | — | — | WO | claimed |
| EP-3022272-A1 | ASPHALTENE-DISSOLVING OIL-EXTERNAL EMULSION FOR ACIDIZATION AND METHODS OF USING THE SAME | Halliburton Energy Services, Inc. (US) | 2016-05-25 | — | — | EP | claimed |
| WO-2016032578-A1 | ACIDIZING COMPOSITIONS INCLUDING AMPHOLYTE POLYMERS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2016-03-03 | — | — | WO | claimed |
| WO-2016018350-A1 | GUANIDINE- OR GUANIDINIUM-CONTAINING COMPOUNDS FOR TREATMENT OF SUBTERRANEAN FORMATIONS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2016-02-04 | — | — | WO | claimed |
| WO-2016010520-A1 | POLYMERIC IONIC LIQUID CLAY CONTROL AGENTS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2016-01-21 | — | — | WO | claimed |
| WO-2015034478-A1 | SCALE-INHIBITING COCRYSTALS FOR TREATMENT OF A SUBTERRANEAN FORMATION | HALLIBURTON ENERGY SERVICES, INC. (US) | 2015-03-12 | — | — | WO | claimed |
| WO-2015023296-A1 | HYDROPHOBICALLY AND HYDROPHILICALLY MODIFIED POLYSACCHARIDES AND METHODS OF USING THE SAME FOR TREATMENT OF A SUBTERRANEAN FORMATION | HALLIBURTON ENERGY SERVICES, INC. (US) | 2015-02-19 | — | — | WO | claimed |
| US-20140352969-A1 | AMPHOLYTE POLYMERS AND METHODS OF TREATING SUBTERRANEAN FORMATIONS WITH THE SAME | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-12-04 | — | — | US | claimed |
| US-7981845-B2 | Partially neutralized polyhydroxy acids for well treatments | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2011-07-19 | — | — | US | claimed |
| WO-2010023602-A1 | PARTIALLY NEUTRALIZED POLYHYDROXY ACIDS FOR WELL TREATMENTS | SCHLUMBERGER CANADA LIMITED (CA) | 2010-03-04 | — | — | WO | claimed |
| US-20100056401-A1 | PARTIALLY NEUTRALIZED POLYHYDROXY ACIDS FOR WELL TREATMENTS | SCHLUMBERGER TECHNOLOGY CORPORATION | 2010-03-04 | — | — | US | claimed |
| US-7225874-B2 | Methods and compositions for reducing the viscosity of treatment fluids used in subterranean operations | HALLIBURTON ENERGY SERVICES, INC. (US) | 2007-06-05 | — | — | US | claimed |
| WO-2007020390-A1 | METHODS AND COMPOSITIONS FOR REDUCING THE VISCOSITY OF TREATMENT FLUIDS USED IN SUBTERRANEAN OPERATIONS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070034376-A1 | Providing a treatment fluid that comprises an aqueous base fluid and a gelling agent; providing a breaker that comprises a hydroquinone component; allowing the breaker to interact with the treatment fluid; and allowing the breaker to at least partially reduce the viscosity of the treatment fluid | HALLIBURTON ENERGY SERVICES, INC. | 2007-02-15 | — | — | US | claimed |
| US-20070037713-A1 | Comprises a gelling agent, the breaker comprising a hydroquinone component and an additional breaker component | HALLIBURTON ENERGY SERVICES, INC. | 2007-02-15 | — | — | US | claimed |