SCHEMBL1977356

SCHEMBL1977356

CCC(O)CC1CC2C=CC1C2

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.45
ALDH1A1 P00352 4/20 0.45
IDO1 P14902 1/20 0.37
TDO2 P48775 1/20 0.37
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
PKM P14618 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
ATM Q13315 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15922747 1.00 KDM4E (0.45) KDM4EALDH1A1IDO1TDO2MEN1
SCHEMBL14117842 0.81 KDM4E (0.43) KDM4EALDH1A1IDO1TDO2MEN1
SCHEMBL10946796 0.80 KDM4E (0.42) KDM4EALDH1A1IDO1TDO2MEN1
SCHEMBL6359572 0.80 IDO1 (0.37) KDM4EALDH1A1IDO1TDO2MEN1
SCHEMBL14309197 0.78 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL465320 0.78 KDM4E (0.47) KDM4EALDH1A1IDO1TDO2MEN1
SCHEMBL18023913 0.77 KDM4E (0.39) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL3364065 0.76 KDM4E (0.37) KDM4EALDH1A1IDO1TDO2MEN1
SCHEMBL32688903 0.76 KDM4E (0.40) KDM4EALDH1A1IDO1TDO2MEN1
SCHEMBL12256142 0.76 KDM4E (0.42) KDM4EALDH1A1IDO1TDO2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102695741-B Norbornene-type polymers having quaternary ammonium functionality PROMERUS LLC 2015-07-08 CN disclosed
WO-2014121008-A1 NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME PROMERUS, LLC (US) 2014-08-07 WO disclosed
US-8765894-B2 Norbornene-type polymers having quaternary ammonium functionality PROMERUS, LLC (US) 2014-07-01 US disclosed
US-8765893-B2 Norbornene-type polymers having quaternary ammonium functionality PROMERUS, LLC (US) 2014-07-01 US disclosed
EP-2510036-A2 NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY Promerus LLC (US) 2012-10-17 EP disclosed
CN-102695741-A Norbornene-type polymers having quaternary ammonium functionality PROMERUS LLC 2012-09-26 CN disclosed
US-20110244368-A1 NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY PROMERUS LLC (US) 2011-10-06 US disclosed
US-20110143260-A1 NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY PROMERUS LLC (US) 2011-06-16 US disclosed
WO-2011072304-A2 NORBORNENE-TYPE POLYMERS HAVING QUATERNARY AMMONIUM FUNCTIONALITY PROMERUS LLC (US) 2011-06-16 WO disclosed