SCHEMBL12256142

SCHEMBL12256142

FC(F)CC1CC2C=CC1C2

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 13/20 0.42
ALDH1A1 P00352 4/20 0.42
TSHR P16473 1/20 0.37
IDO1 P14902 1/20 0.35
TDO2 P48775 1/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HTT P42858 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
PKM P14618 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19689430 0.82 KDM4E (0.44) KDM4EALDH1A1TSHRIDO1TDO2
SCHEMBL465320 0.80 KDM4E (0.47) KDM4EALDH1A1TSHRIDO1TDO2
SCHEMBL10946796 0.78 KDM4E (0.42) KDM4EALDH1A1TSHRIDO1TDO2
SCHEMBL24355085 0.78 KDM4E (0.39) KDM4EALDH1A1TSHRIDO1TDO2
SCHEMBL15922747 0.76 KDM4E (0.45) KDM4EALDH1A1TSHRIDO1TDO2
SCHEMBL1977356 0.76 KDM4E (0.45) KDM4EALDH1A1TSHRIDO1TDO2
SCHEMBL7531435 0.75 KDM4E (0.43) KDM4EALDH1A1TSHRIDO1TDO2
SCHEMBL13346726 0.75 KDM4E (0.43) KDM4EALDH1A1TSHRIDO1TDO2
SCHEMBL2508452 0.75 KDM4E (0.40) KDM4EALDH1A1TSHRIDO1TDO2
SCHEMBL14117842 0.75 KDM4E (0.43) KDM4EALDH1A1TSHRIDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8709704-B2 Pattern forming method using developer containing organic solvent and rinsing solution for use in the pattern forming method FUJIFILM CORPORATION (JP) 2014-04-29 US disclosed
US-20120322007-A1 PATTERN FORMING METHOD, CHEMICAL AMPLIFICATION RESIST COMPOSITION AND RESIST FILM FUJIFILM CORPORATION (JP) 2012-12-20 US disclosed
US-20110229832-A1 PATTERN FORMING METHOD USING DEVELOPER CONTAINING ORGANIC SOLVENT AND RINSING SOLUTION FOR USE IN THE PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2011-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110229832-A1 PATTERN FORMING METHOD USING DEVELOPER CONTAINING ORGANIC SOLVENT AND RINSING SOLUTION FOR USE IN THE PATTERN FORMING METHOD RER1, RARA, RARG KDM4E 3329/4885ALDH1A1 1783/4885TSHR 2489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.