Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.55 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19777693 | 1.00 | PRMT6 (0.55) | PRMT6P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL13396559 | 1.00 | PRMT6 (0.55) | PRMT6P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL11685620 | 0.95 | PRMT6 (0.57) | PRMT6P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL29672351 | 0.95 | PRMT6 (0.57) | PRMT6P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL16206177 | 0.95 | PRMT6 (0.57) | PRMT6P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL13020687 | 0.95 | PRMT6 (0.57) | PRMT6P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL12700006 | 0.94 | PRMT6 (0.54) | PRMT6ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL16203602 | 0.91 | PRMT6 (0.53) | PRMT6P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL3465905 | 0.90 | LMNA (0.51) | PRMT6P2RX3P2RX4P2RX2ADORA1 | |
| SCHEMBL29479253 | 0.90 | LMNA (0.57) | ADORA1ADORA3ADORA2AADORA2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292215-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE | SPEROVIE BIOSCIENCES, INC. | 2019-09-26 | — | — | US | disclosed |
| WO-2018013908-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE | SPEROVIE BIOSCIENCES, INC. (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292215-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE | STING1, CGAS, MYD88 | PRMT6 1890/4885P2RX3 222/4885P2RX4 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.