Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.41 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 2/20 | 0.39 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.38 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DTYMK | P23919 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389679 | 1.00 | P2RX3 (0.41) | P2RX3P2RX4P2RX2RNASE1TYMS | |
| SCHEMBL19777697 | 1.00 | P2RX3 (0.41) | P2RX3P2RX4P2RX2RNASE1TYMS | |
| SCHEMBL19780271 | 1.00 | P2RX3 (0.41) | P2RX3P2RX4P2RX2RNASE1TYMS | |
| SCHEMBL21389676 | 0.96 | P2RX3 (0.41) | P2RX3P2RX4P2RX2RNASE1TYMS | |
| SCHEMBL21389670 | 0.92 | TYMP (0.38) | P2RX3P2RX4P2RX2RNASE1TYMS | |
| SCHEMBL19777696 | 0.92 | TYMP (0.38) | P2RX3P2RX4P2RX2RNASE1TYMS | |
| SCHEMBL21389678 | 0.88 | TYMP (0.38) | P2RX3P2RX4P2RX2RNASE1TYMS | |
| SCHEMBL19777694 | 0.88 | TYMP (0.38) | P2RX3P2RX4P2RX2RNASE1TYMS | |
| SCHEMBL21389685 | 0.83 | P2RX3 (0.34) | P2RX3P2RX4P2RX2TYMSP2RX6 | |
| SCHEMBL21636130 | 0.80 | RNASE1 (0.44) | RNASE1F2POLBDTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013908-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE | SPEROVIE BIOSCIENCES, INC. (US) | 2018-01-18 | — | — | WO | disclosed |