Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 10/20 | 0.71 |
| ▸ | GSK3A | P49840 | 10/20 | 0.71 |
| ▸ | CDK5 | Q00535 | 9/20 | 0.71 |
| ▸ | GSK3B | P49841 | 9/20 | 0.71 |
| ▸ | CDK2 | P24941 | 9/20 | 0.71 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.71 |
| ▸ | KDR | P35968 | 8/20 | 0.71 |
| ▸ | LIMK1 | P53667 | 8/20 | 0.71 |
| ▸ | CHEK2 | O96017 | 8/20 | 0.71 |
| ▸ | MAPK9 | P45984 | 8/20 | 0.71 |
| ▸ | CSNK1D | P48730 | 8/20 | 0.71 |
| ▸ | CDK1 | P06493 | 8/20 | 0.71 |
| ▸ | RPS6KA3 | P51812 | 7/20 | 0.71 |
| ▸ | DAPK3 | O43293 | 7/20 | 0.71 |
| ▸ | PRKACA | P17612 | 7/20 | 0.71 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.71 |
| ▸ | PLK4 | O00444 | 7/20 | 0.71 |
| ▸ | SGK2 | Q9HBY8 | 7/20 | 0.71 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.71 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19769169 | 0.89 | GSK3A (0.56) | PIM1GSK3ACDK5GSK3BCDK2 | |
| SCHEMBL5555786 | 0.84 | PIM1 (0.78) | PIM1GSK3ACDK5GSK3BCDK2 | |
| SCHEMBL7055360 | 0.83 | PIM1 (0.76) | PIM1GSK3ACDK5GSK3BCDK2 | |
| SCHEMBL7055380 | 0.83 | PIM1 (1.00) | PIM1GSK3ACDK5GSK3BCDK2 | |
| SCHEMBL7050653 | 0.83 | GSK3A (1.00) | PIM1GSK3ACDK5GSK3BCDK2 | |
| SCHEMBL7056743 | 0.83 | GSK3A (1.00) | PIM1GSK3ACDK5GSK3BCDK2 | |
| SCHEMBL19769135 | 0.82 | PIM1 (0.71) | PIM1GSK3ACDK5GSK3BCDK2 | |
| SCHEMBL5550778 | 0.82 | PIM1 (0.78) | PIM1GSK3ACDK5GSK3BCDK2 | |
| SCHEMBL5950999 | 0.80 | MAP3K8 (0.68) | PIM1GSK3ACDK5GSK3BCDK2 | |
| SCHEMBL7057944 | 0.80 | PIM1 (0.80) | PIM1GSK3ACDK5GSK3BCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180015077-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTION | NAKAMURA, ROBERT | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015077-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTION | CD4, CCR5, MMP8 | PIM1 1098/4885GSK3A 1892/4885CDK5 1897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.