Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | ACACA | Q13085 | 3/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.37 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22072403 | 0.84 | ACP1 (0.46) | ACP1MAP4K4GLAP2RX3MAPT | |
| SCHEMBL19781252 | 0.83 | GLA (0.41) | ACP1GLAP2RX3MAPTALDH1A1 | |
| SCHEMBL22071863 | 0.83 | ACP1 (0.42) | ACP1ACACBACACAMAP4K4GLA | |
| SCHEMBL22072388 | 0.81 | ACP1 (0.40) | ACP1ACACBACACAMAP4K4GLA | |
| SCHEMBL22072402 | 0.80 | KDM4E (0.44) | ACP1ACACBACACAGLAMAPT | |
| SCHEMBL19781774 | 0.80 | ACP1 (0.45) | ACP1ACACBACACAMAP4K4GLA | |
| SCHEMBL22072401 | 0.77 | MAPT (0.46) | ACP1GLAP2RX3MAPTALDH1A1 | |
| SCHEMBL22032880 | 0.75 | ACP1 (0.41) | ACP1GLAP2RX3MAPTALDH1A1 | |
| SCHEMBL15213071 | 0.73 | P2RX3 (0.43) | ACP1GLAP2RX3MAPTALDH1A1 | |
| SCHEMBL19781521 | 0.73 | GLA (0.42) | ACP1GLAP2RX3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013430-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ARENAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2018-01-18 | — | — | WO | disclosed |