Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.40 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22072401 | 0.85 | MAPT (0.46) | ACP1GLAMAPTRAB9AKMT2A | |
| SCHEMBL19781521 | 0.84 | GLA (0.42) | ACP1GLAMAPTRAB9AKMT2A | |
| SCHEMBL19781130 | 0.80 | ACP1 (0.42) | ACP1GLAMAPTRAB9AKMT2A | |
| SCHEMBL19781532 | 0.78 | ACP1 (0.46) | ACP1GLAMAPTRAB9AKMT2A | |
| SCHEMBL22072403 | 0.78 | ACP1 (0.46) | ACP1GLAMAPTRAB9AKMT2A | |
| SCHEMBL22071863 | 0.77 | ACP1 (0.42) | ACP1GLAMAPTRAB9AKMT2A | |
| SCHEMBL19781252 | 0.77 | GLA (0.41) | ACP1GLAMAPTRAB9AKMT2A | |
| SCHEMBL15213071 | 0.75 | P2RX3 (0.43) | ACP1GLAMAPTRAB9AKMT2A | |
| SCHEMBL22033693 | 0.74 | P2RX3 (0.43) | ACP1GLAMAPTRAB9AKMT2A | |
| SCHEMBL22032818 | 0.74 | SYK (0.43) | ACP1GLAMAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013430-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ARENAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2018-01-18 | — | — | WO | disclosed |