Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19768951 | 0.80 | CYP1A2 (0.39) | CYP1A2CYP2D6CYP2C9HPGDMAPK1 | |
| SCHEMBL26420702 | 0.80 | CYP1A2 (0.39) | CYP1A2CYP2D6CYP2C9HPGDMAPK1 | |
| SCHEMBL11762546 | 0.79 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C9HPGDMAPK1 | |
| SCHEMBL19880427 | 0.78 | CYP1A2 (0.37) | CYP1A2CYP2D6CYP2C9HPGDMAPK1 | |
| SCHEMBL19779774 | 0.78 | CYP1A2 (0.37) | CYP1A2CYP2D6CYP2C9HPGDMAPK1 | |
| SCHEMBL19008946 | 0.74 | CYP1A2 (0.42) | CYP1A2CYP2D6CYP2C9HPGDMAPK1 | |
| SCHEMBL25565979 | 0.72 | NCF1 (0.36) | CYP1A2CYP2D6 | |
| SCHEMBL25565977 | 0.72 | NCF1 (0.36) | CYP1A2CYP2D6 | |
| SCHEMBL25565978 | 0.72 | NCF1 (0.36) | CYP1A2CYP2D6 | |
| SCHEMBL23492771 | 0.71 | PLA2G1B (0.36) | CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013676-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2018-01-18 | — | — | WO | disclosed |