Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25565977 | 1.00 | NCF1 (0.36) | NCF1PGRDRD2DRD3MEN1 | |
| SCHEMBL25565978 | 1.00 | NCF1 (0.36) | NCF1PGRDRD2DRD3MEN1 | |
| SCHEMBL25565975 | 0.91 | NCF1 (0.42) | NCF1PGRDRD2DRD3 | |
| SCHEMBL15473865 | 0.88 | NCF1 (0.41) | NCF1PGRMEN1KMT2ACYP1A2 | |
| SCHEMBL13006566 | 0.79 | MEN1 (0.40) | NCF1DRD3MEN1KMT2ACYP2D6 | |
| SCHEMBL13361145 | 0.78 | NCF1 (0.48) | NCF1 | |
| SCHEMBL25565980 | 0.78 | NCF1 (0.41) | NCF1PGRDRD2DRD3BCHE | |
| SCHEMBL10035081 | 0.78 | DRD2 (0.40) | DRD2DRD3CYP1A2CYP2D6 | |
| SCHEMBL27397553 | 0.76 | GNAO1 (0.42) | NCF1PGRDRD2DRD3 | |
| SCHEMBL23841454 | 0.75 | NCF1 (0.45) | NCF1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083194-A1 | WEE1 PROTEIN KINASE DEGRADATION AGENT AND USE THEREOF | 杭州格博生物医药有限公司 | 2023-05-19 | — | — | WO | disclosed |