Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781618 | 0.81 | PDE5A (0.30) | PDE5A | |
| SCHEMBL31200166 | 0.73 | SMN1; SMN2 (0.47) | KDM4E | |
| SCHEMBL19510490 | 0.72 | KDM4E (0.34) | KDM4EIDO1 | |
| Bromide SCHEMBL19510409 | 0.71 | KDM4E (0.33) | KDM4EIDO1 | |
| SCHEMBL13745072 | 0.68 | MAPK14 (0.39) | — | |
| SCHEMBL25149807 | 0.67 | MYC (0.40) | KDM4E | |
| SCHEMBL8378700 | 0.64 | CSNK1A1 (0.36) | KDM4EIDO1 | |
| SCHEMBL5572841 | 0.64 | CDK8 (0.41) | KDM4EIDO1 | |
| SCHEMBL20713266 | 0.64 | SMN1; SMN2 (0.39) | KDM4E | |
| SCHEMBL15230214 | 0.64 | KDM4E (0.32) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013430-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ARENAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2018-01-18 | — | — | WO | disclosed |