Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 17/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665074 | 0.72 | ALDH1A1 (0.42) | SMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL19781618 | 0.67 | PDE5A (0.30) | — | |
| SCHEMBL15230214 | 0.65 | KDM4E (0.32) | KDM4E | |
| SCHEMBL25235622 | 0.63 | KDM4E (0.44) | SMN1; SMN2PBRM1L3MBTL1BRD4KDM4E | |
| SCHEMBL254009 | 0.62 | GAA (0.44) | SMN1; SMN2PBRM1L3MBTL1 | |
| SCHEMBL16885105 | 0.61 | GAA (0.39) | SMN1; SMN2KDM4E | |
| SCHEMBL5930819 | 0.61 | EGLN2 (0.42) | — | |
| SCHEMBL19761029 | 0.61 | LMNA (0.38) | L3MBTL1 | |
| SCHEMBL18323659 | 0.60 | SMN1; SMN2 (0.44) | SMN1; SMN2PBRM1L3MBTL1BRD4KDM4E | |
| SCHEMBL15314290 | 0.60 | SMN1; SMN2 (0.44) | SMN1; SMN2PBRM1L3MBTL1BRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709722-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233547-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |