Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10970208 | 0.91 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNAHPGDPOLB | |
| SCHEMBL10973042 | 0.88 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNAHPGDPOLB | |
| SCHEMBL17761121 | 0.86 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNAHPGDPOLB | |
| SCHEMBL24305911 | 0.86 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNAHPGDPOLB | |
| SCHEMBL7301329 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TSHRLMNAHPGDPOLB | |
| SCHEMBL16526226 | 0.84 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNAHPGDPOLB | |
| SCHEMBL18797457 | 0.83 | POLB (0.68) | ALDH1A1TSHRLMNAHPGDPOLB | |
| SCHEMBL7303919 | 0.82 | ALDH1A1 (0.66) | ALDH1A1TSHRLMNAHPGDPOLB | |
| SCHEMBL10972734 | 0.82 | ALDH1A1 (0.63) | ALDH1A1TSHRLMNAHPGDPOLB | |
| SCHEMBL16116944 | 0.82 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889894-B2 | Compounds for use in therapy | BANGOR UNIVERSITY (GB) | 2014-11-18 | — | — | US | disclosed |
| US-8728515-B2 | Adjuvants for use in vaccination | BANGOR UNIVERSITY (GB) | 2014-05-20 | — | — | US | disclosed |
| EP-2620158-A1 | Adjuvants for use in vaccination | Bangor University (GB) | 2013-07-31 | — | — | EP | disclosed |
| US-20110150981-A1 | Compounds for Use in Therapy | BANGOR UNIVERSITY (GB) | 2011-06-23 | — | — | US | disclosed |
| US-20110142916-A1 | Adjuvants for Use in Vaccination | BANGOR UNIVERSITY (GB) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110142916-A1 | Adjuvants for Use in Vaccination | NR1H3, NR1H2, INTS6 | ALDH1A1 4317/4885TSHR 46/4885LMNA 4409/4885 |
| US-20110150981-A1 | Compounds for Use in Therapy | CD4, MSR1, TST | ALDH1A1 1837/4885TSHR 38/4885LMNA 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.