SCHEMBL1978201

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30939585	1.00	SMN1; SMN2 (0.51)	SMN1; SMN2LMNAMAPTHTTALDH1A1
	SCHEMBL1191959	0.86	AR (0.55)	SMN1; SMN2LMNAHTTALDH1A1TSHR
	SCHEMBL1192049	0.83	AR (0.58)	SMN1; SMN2LMNAHTTALDH1A1RAB9A
	SCHEMBL1773418	0.79	AR (0.54)	SMN1; SMN2LMNAMAPTALDH1A1MMP13
	SCHEMBL1979660	0.78	AR (0.54)	AR
	SCHEMBL9662714	0.77	MAPT (0.51)	SMN1; SMN2LMNAMAPTHTTALDH1A1
	SCHEMBL21610217	0.77	LMNA (0.43)	SMN1; SMN2LMNAMAPTHTTALDH1A1
	SCHEMBL24350550	0.76	LMNA (0.42)	SMN1; SMN2LMNAMAPTHTTALDH1A1
	SCHEMBL1772863	0.76	AR (0.59)	SMN1; SMN2LMNAHTTRAB9ANPSR1
	SCHEMBL1982664	0.75	AR (0.47)	SMN1; SMN2LMNAHTTALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.