⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781520 | 0.85 | SSTR2 (0.31) | — | |
| SCHEMBL19782071 | 0.80 | KDM1A (0.33) | — | |
| SCHEMBL19780074 | 0.80 | HOGA1 (0.35) | — | |
| SCHEMBL19768947 | 0.79 | — | — | |
| SCHEMBL19779746 | 0.77 | MAN1B1 (0.35) | — | |
| SCHEMBL21884006 | 0.74 | — | — | |
| SCHEMBL19880460 | 0.70 | — | — | |
| SCHEMBL25105137 | 0.69 | NCF1 (0.35) | — | |
| SCHEMBL25105138 | 0.69 | NCF1 (0.35) | — | |
| SCHEMBL25105161 | 0.69 | NCF1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013676-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2018-01-18 | — | — | WO | disclosed |