Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782876 | 0.86 | GSK3B (0.54) | GSK3BLMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL12091718 | 0.79 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2L3MBTL1MAPTKMT2A | |
| SCHEMBL29601272 | 0.79 | GSK3B (0.58) | GSK3BLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8190351 | 0.79 | GSK3B (0.58) | GSK3BLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30421407 | 0.79 | GSK3B (0.58) | GSK3BLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7206946 | 0.78 | GSK3B (0.54) | GSK3BLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29601629 | 0.78 | GSK3B (0.66) | GSK3BLMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL15993270 | 0.78 | GSK3B (0.66) | GSK3BLMNAALDH1A1SMN1; SMN2TSHR | |
| Bromide SCHEMBL15993360 | 0.78 | GSK3B (0.57) | GSK3BLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL19782864 | 0.78 | GSK3B (0.57) | GSK3BLMNAALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013508-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE (US) | 2018-01-18 | — | — | WO | disclosed |