Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886976 | 0.83 | POLB (0.45) | ALDH1A1NR4A2CYP3A4LMNANOS3 | |
| SCHEMBL30124712 | 0.83 | POLB (0.45) | ALDH1A1NR4A2CYP3A4LMNANOS3 | |
| SCHEMBL9382622 | 0.81 | NR4A2 (0.44) | ALDH1A1NR4A2CYP3A4LMNANOS3 | |
| SCHEMBL31330045 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1NR4A2CYP3A4LMNA | |
| SCHEMBL31330044 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1NR4A2CYP3A4LMNA | |
| SCHEMBL17595014 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP3A4NOS3NOS1NOS2 | |
| SCHEMBL1279214 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1CYP3A4LMNANOS3 | |
| SCHEMBL3808172 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1NR4A2LMNANOS3 | |
| SCHEMBL4797238 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1CYP3A4MAPTHSP90AA1 | |
| SCHEMBL19754831 | 0.74 | HSP90AA1 (0.41) | ALDH1A1NR4A2CYP3A4LMNANOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101780-A1 | PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF | OCTANT, INC. (US) | 2025-05-15 | — | — | WO | disclosed |
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |