Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.33 |
| ▸ | GLA | P06280 | 3/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783855 | 0.88 | ADORA2A (0.40) | TLR8ADORA2BCYP3A4CYP2C9PDE10A | |
| SCHEMBL19783859 | 0.86 | TLR8 (0.37) | TLR8ADORA2BALDH1A1PDE10AESR2 | |
| SCHEMBL21422279 | 0.85 | ALDH1A1 (0.39) | TLR8LMNACYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL19783293 | 0.85 | TLR8 (0.36) | TLR8ADORA2BESR2ADORA2AADORA1 | |
| SCHEMBL19784123 | 0.85 | TLR8 (0.37) | TLR8ADORA2BALDH1A1MAT2AESR2 | |
| SCHEMBL21422263 | 0.85 | TLR8 (0.37) | TLR8ADORA2BPDE10AMAT2AESR2 | |
| SCHEMBL19783857 | 0.84 | TLR8 (0.36) | TLR8ADORA2BLMNAALDH1A1MAT2A | |
| SCHEMBL19784121 | 0.84 | HIF1A (0.39) | TLR8ALDH1A1CYP3A4MAT2A | |
| SCHEMBL19783990 | 0.84 | TLR8 (0.44) | TLR8ADORA2BCYP3A4MAT2AHTT | |
| SCHEMBL19784119 | 0.82 | USP2 (0.39) | TLR8LMNAPOLBCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484877-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-20190297887-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-03 | — | — | US | disclosed |
| WO-2018011111-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190297887-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | DDT, BCHE, ACHE | TLR8 3552/4885ADORA2B 4249/4885LMNA 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.