Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782674 | 0.79 | KMT2A (0.33) | KMT2A | |
| SCHEMBL21379385 | 0.77 | KMT2A (0.36) | KMT2ANPC1RAB9A | |
| SCHEMBL21379691 | 0.74 | NPC1 (0.34) | KMT2ANPC1RAB9A | |
| SCHEMBL19783011 | 0.74 | ALDH1A1 (0.33) | NPC1RAB9A | |
| SCHEMBL19782676 | 0.69 | MAPT (0.35) | — | |
| SCHEMBL21395608 | 0.68 | ALDH1A1 (0.38) | KMT2ANPC1RAB9A | |
| SCHEMBL30189893 | 0.68 | ALDH1A1 (0.38) | KMT2ANPC1RAB9A | |
| SCHEMBL28941149 | 0.67 | NPC1 (0.34) | NPC1RAB9A | |
| SCHEMBL21379620 | 0.67 | KMT2A (0.34) | KMT2ANPC1RAB9A | |
| SCHEMBL21379670 | 0.65 | MAPT (0.39) | KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |