Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782676 | 0.90 | MAPT (0.35) | ALDH1A1 | |
| SCHEMBL19783779 | 0.79 | KMT2A (0.31) | KMT2A | |
| SCHEMBL19783795 | 0.77 | KMT2A (0.33) | KMT2AALDH1A1 | |
| SCHEMBL30189793 | 0.77 | KMT2A (0.33) | KMT2AALDH1A1 | |
| SCHEMBL21379620 | 0.76 | KMT2A (0.34) | KMT2AALDH1A1 | |
| SCHEMBL19782704 | 0.74 | ALDH1A1 (0.32) | KMT2AALDH1A1 | |
| SCHEMBL19783656 | 0.73 | USP9X (0.33) | KMT2AALDH1A1 | |
| SCHEMBL21396119 | 0.66 | ALDH1A1 (0.36) | KMT2AALDH1A1 | |
| SCHEMBL30189887 | 0.66 | ALDH1A1 (0.36) | KMT2AALDH1A1 | |
| SCHEMBL19783511 | 0.66 | KMT2A (0.38) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |