SCHEMBL1978383

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30939529	1.00	POLB (0.34)	POLBL3MBTL1MCHR1GPR119NPSR1
	SCHEMBL30939671	0.89	POLB (0.33)	POLBL3MBTL1MCHR1NPSR1DRD1
	SCHEMBL1978645	0.89	POLB (0.33)	POLBL3MBTL1MCHR1NPSR1DRD1
	SCHEMBL22026376	0.89	POLB (0.33)	POLBL3MBTL1MCHR1NPSR1DRD1
	SCHEMBL1981120	0.88	CHRM2 (0.34)	POLBL3MBTL1GPR119NPSR1KCNH2
	SCHEMBL1982377	0.88	DRD1 (0.38)	POLBMCHR1NPSR1DRD1
	SCHEMBL20567334	0.88	NPSR1 (0.39)	POLBNPSR1MAPK1MMP13
	SCHEMBL20599031	0.88	DRD1 (0.38)	POLBMCHR1NPSR1DRD1
	SCHEMBL1980580	0.88	DRD1 (0.38)	POLBMCHR1NPSR1DRD1
	SCHEMBL30939542	0.88	DRD1 (0.38)	POLBMCHR1NPSR1DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.